Iodine promoted α-hydroxylation of ketones.
نویسندگان
چکیده
A novel method for α-hydroxylation of ketones using substoichiometric amount of iodine under metal-free conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful precursors. α-Hydroxylation of diketones and triketones are illustrated. This strategy provides a novel, efficient, mild and inexpensive method for α-hydroxylation of aryl ketones using a sub-stoichiometric amount of molecular iodine.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 24 شماره
صفحات -
تاریخ انتشار 2015